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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10160 | 11β-HSD1-IN-1 | Dehydrogenase | |
11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain. | |||
T60149 | 11β-HSD1-IN-11 | Dehydrogenase | |
11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13 μM, respectively. 11β-Hsvd1-in-11 is a compound used as a che... | |||
T60203 | INCB13739 | ||
INCB13739 is an orally active, potent, selective, and tissue-specific inhibitor of 11β-HSD1 (11β-hydroxysteroid dehydrogenase 1), demonstrating IC50 values of 3.2 nM (11β-HSD1 enzymatic) and 1.1 nM (11β-HSD1 PBMC). It is... | |||
T61593 | 11β-HSD1-IN-6 | ||
11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs). These enzymes are responsible for catalyzing the conversion of the active glucocorticoids, corticosterone or cortisol, to their ... | |||
T80817 | WAY-328127 | ||
WAY-328127 is an active molecule, exhibiting an inhibitory effect on the (11β-hydroxysteroid dehydrogenase type 1) [(11β-HSD1)] enzyme. This modulation potentially leads to therapeutic applications in metabolic disorders... | |||
T70763 | KR-67607 | ||
KR-67607, also known as NTX-101 is novel selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor. KR-67607 decreased 4-hydroxynonenal expression and increased antioxidant and mucus secretion in BAC-treated rat ... |